Enclomiphene Therapy

What is Enclomiphene?

Enclomiphene citrate, also known simply as enclomiphene, is a nonsteroidal selective estrogen receptor modulator (SERM). It is structurally similar to clomiphene citrate but is the pure enantiomer (single stereoisomer) of clomiphene. Enclomiphene is primarily used to treat hypogonadism and low testosterone levels in men.

How does Enclomiphene work:

Enclomiphene works by acting on the hypothalamus and pituitary gland in the brain. It binds to estrogen receptors in these areas, blocking the negative feedback mechanism that estrogen usually exerts on the production of gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH). This blockade leads to increased secretion of GnRH, which stimulates the pituitary gland to release more LH and follicle-stimulating hormone (FSH). The increased LH levels in turn stimulate the Leydig cells in the testes to produce more testosterone.

Who Can Benefit from Enclomiphene therapy?

This therapy is ideal for individuals who:

  • Have low testosterone (Low T) but want to stimulate natural production instead of using TRT.

  • Are recovering from TRT (Post-Cycle Therapy - PCT) and need to restore testicular function.

  • Want to boost fertility while increasing testosterone levels.

  • Athletes or bodybuilders looking to maintain natural testosterone production after using performance enhancers.

  • Men experiencing symptoms of Low T, such as low energy, reduced libido, brain fog, or loss of muscle mass.

Enclomiphene Dosing Protocol

Standard Dosing

  • Oral Dosage:

    • Typical Starting Dose: 6.25 mg daily

    • Adjustable Dose: Can be increased between 12.5 to 25 mg daily if needed, based on lab results and symptom improvement.

  • Cycle Duration:

    • Short-Term Use: 6-12 weeks for boosting natural testosterone.

    • Long-Term Use: Some individuals use it continuously under medical supervision for sustained testosterone production.

  • Non-Steroidal Nature: Enclomiphene is non-steroidal, which may be preferable for individuals concerned about the potential side effects of testosterone replacement therapy (TRT).

    Oral Intake: Enclomiphene is taken orally, making it convenient and easy to administer compared to other forms of testosterone therapy that may require injections or transdermal patches. This can improve adherence to treatment regimens.

    Boosts Testosterone Production: Enclomiphene effectively increases endogenous testosterone production in men with hypogonadism or low testosterone levels.

    Preserves Fertility: Unlike exogenous testosterone therapy, which can suppress sperm production, enclomiphene preserves or enhances sperm production due to its selective action on the hypothalamus-pituitary-testes axis.

    Improves Symptoms of Hypogonadism: It helps alleviate symptoms associated with low testosterone, such as fatigue, low libido, erectile dysfunction, and mood disturbances.

    Bone Health: Increasing testosterone levels can help improve bone density and reduce the risk of osteoporosis.

  • Hot Flashes: A common side effect characterized by sudden feelings of warmth, often accompanied by sweating.

    Headaches: Some men may experience headaches during treatment with enclomiphene.

    Mood Changes: Mood swings or irritability can occur, though these are generally less common compared to exogenous testosterone therapies.

    Visual Disturbances: Rarely, men may experience blurred vision or changes in color perception.

    Gastrointestinal Discomfort: Mild symptoms such as nausea or abdominal discomfort can occur in some individuals.

    Lowered IGF-1 Levels: Enclomiphene therapy may lead to decreased levels of Insulin-like Growth Factor 1 (IGF-1). IGF-1 is important for growth and metabolism, and lower levels may affect muscle growth and overall metabolic health in men.

Simple, Easy Pricing.

No hidden costs or fees, ever.

Starting Doses 0.25-2.25 mg/week

Black fabric with folds

Enclomiphene Therapy

$150

/Month

Pricing* Includes:

  • Enclomiphene Citrate Oral Capsule

  • Shipping

  • Supplies

  • Follow-Up Labs

  • Follow-Up Telehealth Visits

  • Nutrition and Exercise Counseling

*Initial Lab-Work Not Included In Price

Additional Therapies That May Interest You

HCG Therapy

HCG Therapy may be used to elevate testosterone levels in individuals who may be experiencing signs and symptoms of low-T. Consult with one of our experts to find out more.

Semaglutide Therapy

Semaglutide may be used as an adjunct therapy with Enclomiphene to expedite fat loss and amplify the benefits of Enclomiphene. Consult with one of our experts for more informations.

Sermorelin Therapy

Sermorelin therapy may be used as an adjunct therapy with Enclomiphene Therapy to further elevate the degree of fat-loss and muscle gain that many patients experience on Enclomiphene, along with an improvement in sleep quality and hair, skin, nail, and joint health. Consult with one of our experts for more information.